Negative Binomial Regression

Overview

Negative binomial regression is another approach to building regression models for count data. It has many advantages over Poisson regression, especially when there is over-dispersion.

The pdf for the negative binomial distribution is

Negative binomial pdf

Let α = 1/ν and p = ν/(ν+μ). Since the mean of a negative binomial distribution is μ = ν (1–p)/p, we can express the variance as ν(1–p)/p2 = μ/p = μ(ν+μ)/ν = μ(1+μ/ν) = μ(1+ αμ); i.e.

var = μ(1 + αμ) = μ + αμ2

From the above, we see that the lower the value of α, the lower the variance. In fact, when α is near zero (i.e. ν is large), then we get the assumption for the Poisson distribution, namely that the mean and the variance are equal.

The resulting regression model is called the negative binomial 2 model (aka the mean dispersion negative binomial model).

There is another negative binomial regression model that is based on the following assumption for the variance

var = μ(1 + α) = μ + αμ

This is called the negative binomial 1 model (aka the constant dispersion negative binomial model), and often this provides a better fit for the data. This is created by setting ν = μ/α instead of ν = 1/α.

Over-dispersion

When the variance is larger than the mean, we have over-dispersion. The Poisson model assumes that we don’t have any over-dispersion. Some possible reasons for over-dispersion are:

  • Missing predictors (i.e. independent variables)
  • Incorrect model
  • Outliers

On this website, we explore the following regression models that can reduce over-dispersion compared to a Poisson regression model:

  • Negative binomial model: as described on this webpage
  • Zero-truncated model: start counting at 1 and not 0. E.g. # of days in the hospital can’t be 0. 
  • Zero-inflated and hurdle models: handle excess zeros using logistic regression

In addition to censoring at zero, we can also left-censor more generally (e.g. no count less than 3) and right-censor (e.g. any count over 8 is counted as 8). We won’t explore these further, however.

Negative Binomial Regression Topics

We discuss the following topics about negative binomial regression:

Links

↑ Regression models

References

Hilbe, J. M. (2014) Modeling count data. Cambridge University Press
https://www.cambridge.org/core/books/modeling-count-data/BFEB3985905CA70523D9F98DA8E64D08

Hintze, J. L. (2007) Negative binomial regression. NCSS
https://www.ncss.com/wp-content/themes/ncss/pdf/Procedures/NCSS/Negative_Binomial_Regression.pdf

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